Pascagoula is a city in Jackson County, Mississippi, United States. It is the principal city of the Pascagoula, Mississippi Metropolitan Statistical Area, as a part of the Gulfport–Biloxi–Pascagoula, Mississippi Combined Statistical Area. The population was 26,200 at the 2000 census. It is the county seat of Jackson County.Pascagoula is a major industrial city of Mississippi, along the Gulf Coast. Prior to World War II, the town was a sleepy fishing village of about 5,000. The population exploded with the war-driven shipbuilding industry. Although the city's population seemed to peak in the late 1970s and early 1980s as Cold War defense spending was at its height, Pascagoula experienced some new growth and development in the years before Hurricane Katrina. Today, Pascagoula is home to the state’s largest employer, Ingalls Shipbuilding, owned by Huntington Ingalls Industries.